SCI07006 2013 COLLOIDAL SCIENCE

General Details

Full Title
COLLOIDAL SCIENCE
Transcript Title
COLLOIDAL SCIENCE
Code
SCI07006
Attendance
N/A %
Subject Area
SCI - Science
Department
LIFE - Life Sciences
Level
07 - NFQ Level 7
Credit
10 - 10 Credits
Duration
Semester
Fee
Start Term
2013 - Full Academic Year 2013-14
End Term
9999 - The End of Time
Author(s)
Tom Patton, James Brennan
Programme Membership
SG_SPHAR_J07 201300 Bachelor of Science in Pharmaceutical Science SG_SPHAD_B07 201800 Bachelor of Science in Pharmaceutical Science SG_SPHAR_B07 201900 Bachelor of Science in Pharmaceutical Science
Description

This module introduces the principles of colloidal science particularly as applied to the pharmaceutical manufacturing industry. Colloid science is concerned with the particles, droplets and bubbles dispersed in bulk phases, and the properties of the interfacial regions around and within them. This course introduces the basic principles of colloid science, including the nature of colloid solutions, the forces involved in colloidal stability, and the link between colloids and surfaces. Colloid science is a critical capability in the design and manufacture of most pharmaceutical and many bio-industry “finished” products, where the interactions between phases and at interfaces are dominant aspects of the system’s behaviour.

Learning Outcomes

On completion of this module the learner will/should be able to;

1.

Report on the terminology and concepts of colloidal systems and their composition

2.

Describe the thermodynamics of Colloidal Systems and the stability of dispersed systems

3.

Discuss capillary forces, wetting/dewetting, interfacial/surface tension, Brownian motion, charged colloids  and electrostatic/steric and depletion forces, colloid self-assembly

4.

Illustrate the principles of rheology and the study of the deformation of matter as apply to colloid dispersions

5.

Explain different processing strategies for structure formation in colloidal systems and understand the challenges in characterising colloidal systems

6.

Examine surface phenomena focusing on the effect of surfactants in colloid formulation

7.

Compare a variety of complex Colloid technologies, materials used to protect active ingredients within formulations

Indicative Syllabus

1.       Report on the terminology and concepts of colloidal systems and their composition: the physical properties of liquids in liquids (emulsions), solids in liquids (dispersions), liquids in gases (aerosols or foams), solid dispersions and biosystems.

2.       Describe the thermodynamics of Colloidal Systems and the stability of dispersed systems.  The practical challenges in assessing stability and the scientific basis of instability through the attractive forces, the nature of charged interfaces and how these interact to provide a stabilising mechanism for colloids.

3.       Discuss capillary forces, wetting/dewetting, interfacial/surface tension, Brownian motion, charged colloids  and electrostatic/steric and depletion forces, self-assembly, the use and effect of additives to control dispersion stability, interactions with the particles and the solvent.

4.       Illustrate the principles of rheology and the study of the deformation of matter resulting from an applied force as apply to colloid and polymer dispersions. The scientific principles involved and the techniques used to produce the desired handling properties of dispersed systems.

5.       Explain different processing strategies for structure formation in colloidal systems and understand the challenges in characterising colloidal systems in terms of particle size, rheology and the commonly used techniques to elicit the relevant information about the system.

6.       Examine surface phenomena (interfaces and surface tension) focusing on the effect of surfactants in formulation. The interfacial phenomena which control the wetting of surfaces, the formation and destabilisation of emulsion systems and how surfactants influence these effects, the chemistry of surfactants, their ability to act in the desired environment and how they control the phase behaviour.

Compare a variety of complex Colloid technologies, materials used to protect active ingredients within formulations to deliver them in a stable and suitable manner to the target sites.

Coursework & Assessment Breakdown

Coursework & Continuous Assessment
40 %
End of Semester / Year Formal Exam
60 %

Coursework Assessment

Title Type Form Percent Week Learning Outcomes Assessed
1 Multiple Choice Continuous Assessment UNKNOWN 20 % OnGoing 1,2,3,4,5,6,7
2 Assignment & Presentation Continuous Assessment UNKNOWN 20 % OnGoing 1,2,3,4,5,6,7
             

End of Semester / Year Assessment

Title Type Form Percent Week Learning Outcomes Assessed
1 Final Exam Final Exam UNKNOWN 60 % End of Term 1,2,3,4,5,6,7
             
             

Full Time Mode Workload


Type Location Description Hours Frequency Avg Workload
Lecture Flat Classroom Theory 5 Weekly 5.00
Group Learning Flat Classroom Project work 1 Weekly 1.00
Independent Learning UNKNOWN Self Study 6 Weekly 6.00
Total Full Time Average Weekly Learner Contact Time 6.00 Hours

Module Resources

Non ISBN Literary Resources

Cosgrove, T., Colloid Science: Principles, Methods and Applications, (2nd Ed), Wiley-Blackwell, 2010,  ISBN-10: 1444320203, ISBN-13: 978-1444320206

 

Other Resources

None

Additional Information

None