SCI06017 2016 Laboratory Skills and Safety for Biomedical Sciences
The module is designed to builds upon key theories and applications in Biology, Chemistry and develop core laboratory skills and safe laboratory practice.
To develop an understanding of the principles, theory and applications of core analytical techniques for the life and health sciences.
On completion of this module the learner will/should be able to;
KNOWLEDGE AND UNDERSTANDING
K1 Explain the principles of Laboratory Safety COSSH and risk assessment.
K2 Describe and discuss microbiological safety hazards.
K3 Describe core technologies used to analyse biomolecules.
K4 Overview the principles and application of analytical separation techniques.
I1 Interpret experimental data logically within a theoretical context.
I2 Use models as an aid to development of scientific understanding.
I3 Application of general chemical principles to specific service needs.
P1 Perform common laboratory procedures safely and summarise and interpret data in a scientific manner.
P2 Use common laboratory apparatus for measurement, containment, reaction and purification of chemical substances, taking appropriate account of COSHH regulations.
T1 Identify the requirements for, organise, and conduct a practical experiment.
T2 Outline how chemical principles can be used to evaluate the use and function of biological molecules.
T3 Compute and evaluate experimental data.
Teaching and Learning Strategies
Online Lectures & tutorials and laboratory practical work, supported by use of molecular models, transparencies, video, WWW and CD-ROM based material including CAL sequences.
Module Assessment Strategies
Lecture topics will be discussed during tutorials held throughout the course. Problem areas identified by the students will be further explained and homework provided to supplement the lecture material covered and to encourage independent learning.
The practical sessions will be designed to: illustrate concepts and applications that are met in the lectures; give training in the use of various techniques and apparatus; in particular fluid handling, microbial culture, aseptic technique, spectrometry, centrifugation and provide experience in the laboratory practices and safe procedures required in working with chemical and biological substances.
- Legislation and Health and Safety guidelines
- Laboratory Risk assessments
- Microbiological safety and waste disposal
- Introduction to spectrometry and applications in drug testing
- Spectroscopic analysis of biomolecules
- Mass spectrometry of biomolecules
- Chromatography and its applications
- Principles and applications of electrophoresis
- Centrifugation methods
- Immunochemical analysis.
Coursework & Assessment Breakdown
|Title||Type||Form||Percent||Week||Learning Outcomes Assessed|
|1||Coursework1||Continuous Assessment||Written Report||25 %||Week 3||1,2,3,4|
|2||Coursework2||Practical||Practical Evaluation||25 %||Week 6||1,2,3,4|
|3||Coursework3||Continuous Assessment||Assessment||25 %||OnGoing||1,2,3,4|
|4||Coursework4||Continuous Assessment||Practical Evaluation||25 %||Week 12||1,2,3,4|
Online Learning Mode Workload
Health and Safety material is available from HMSO and government agency websites
Health & Safety at Work Order (NI)1978 (HSW),
Control of Substances Hazardous to Health (NI) 2000
Safe Working and the Prevention of Infection in Clinical Laboratories
Management of Health and Safety at Work Regulations (NI) 1992
Denniston, JD., Topping J.J. and Caret RL (2006). General, Organic and Biochemistry (5th edition), Boston McGraw Hill
Reed R., Holmes D., Weyers J and Jones A. (2003) Practical Skills in Biomolecular Sciences (2nd edition) Pearson Prentice Hall