PHRM07012 2019 ACTIVE INGREDIENT SYNTHESIS

General Details

Full Title
ACTIVE INGREDIENT SYNTHESIS
Transcript Title
ACTIVE INGREDIENT SYNTHESIS
Code
PHRM07012
Attendance
75 %
Subject Area
PHRM - Pharmaceutical Science
Department
LIFE - Life Sciences
Level
07 - NFQ Level 7
Credit
05 - 05 Credits
Duration
Semester
Fee
Start Term
2019 - Full Academic Year 2019-20
End Term
9999 - The End of Time
Author(s)
Declan Shelly
Programme Membership
SG_SPHAR_B07 201900 Bachelor of Science in Pharmaceutical Science SG_SPHAR_H08 201900 Bachelor of Science (Honours) in Pharmaceutical Science
Description

This module involves the synthesis of a range of Active Pharmaceutical Ingredients and associated regulatory aspects of the process. 

Learning Outcomes

On completion of this module the learner will/should be able to;

1.

Demonstrate competence in the application of a range of organic chemical synthetic techniques to the production of some common active pharmaceutical ingredients.

2.

Analyse some standard synthetic methods and use these to  generate manufacturing documentation in line with cGMP.

3.

Determine quantities of starting materials as well as relevant glassware and equipment required for each synthesis

4.

Generate and follow Standard Operating Procedures (SOP's) in the use of some standard laboratory equipment . 

5.

 Record and report on the synthetic method, including any deviations or variations to the process. 

6.

While working as a member of a group, evaluate the risks associated with each synthetic method and understand how to mitigate against these risks

Teaching and Learning Strategies

This module will be delivered full-time. It will consist of a series of laboratory practicals culminating in the synthesis of selected API's.

Moodle will be used as a repository of educational resources.

Module Assessment Strategies

Students will be assessed based on laboratory performance and results. Further assessment methods include a series of pre- and post laboratory assessments as well as Moodle based multiple choice and short answer questions.

Repeat Assessments

Students may repeat Continuous Assessment as required

Module Dependencies

Prerequisites
None
Co-requisites
None
Incompatibles
None

Indicative Syllabus

This module encompasses  API synthesis

Practical sessions will include,

Generation of Standard Operating Procedures (SOP's)

Active Pharmaceutical Ingredient (API) synthesis

Emphasis throughout is on awareness of GMP / GLP requirements in a pharmaceutical environment.

Coursework & Assessment Breakdown

Coursework & Continuous Assessment
100 %

Coursework Assessment

Title Type Form Percent Week Learning Outcomes Assessed
1 Practical Evaluation Performance in laboratory sessions Formative Practical Evaluation - % OnGoing 1,2,3,4,5,6
2 Group Project Maufacturing processing and reporting Continuous Assessment Group Project 100 % OnGoing 1,2,3,4,5,6
             

Full Time Mode Workload


Type Location Description Hours Frequency Avg Workload
Laboratory Practical Science Laboratory Laboratory Practical 3 Weekly 3.00
Independent Learning Not Specified Self Study 3 Weekly 3.00
Total Full Time Average Weekly Learner Contact Time 3.00 Hours

Module Resources