HLTH06049 2020 Biology of Disease

General Details

Full Title
Biology of Disease
Transcript Title
Biology of Disease
N/A %
Subject Area
HLTH - Health Studies
HEAL - Health & Nutritional Sciences
06 - NFQ Level 6
05 - 05 Credits
Start Term
2020 - Full Academic Year 2020-21
End Term
9999 - The End of Time
Thomas Smyth, Margaret Doherty
Programme Membership
SG_SINFO_B07 202000 Bachelor of Science in Health and Medical Information Science SG_SINFO_C06 202000 Higher Certificate in Science in Health and Medical Information Science

This module aims to introduce the mechanisms associated with the development, progression, manifestation and complications of human disease. The general topics covered include but are not limited to: the nature and causes of cell injury and death; adaptive cellular changes; inflammation, healing and repair, gastrointestinal diseases, genetic diseases, cardiovascular disease and common cancers.

Learning Outcomes

On completion of this module the learner will/should be able to;


Classify each respective type of disease which affect the major biological systems


Outline the aetiology, pathogenesis, macroscopic and microscopic pathologic feature of the major diseases of each system


Relate the clinical signs and symptoms with the underlying pathologic process


Outline and discuss the major risk factors, complications and prognosis of these major diseases

Teaching and Learning Strategies

This module provides various modes of engagement, representation and expression for the student via online lectures, videos, tutorials, and clinical case studies. Tutorial sessions will be used to both review and reinforce learning, and provide guidance for assessment. Clinical scenario problem-solving exercises will be given to promote mechanisms of disease with clinical practice and provide an opportunity to improve confidence in diagnostic reasoning. Any terminologies will be clarified for the student via an online dictionary of terms. Feedback will be given in a timely manner thus enhancing the capacity for self-monitoring by the student.

Module Assessment Strategies

1 X Moodle Quiz, weekly online clinical scenario problem-solving exercises which will be completed and submitted at the end of each workshop within the module.

Repeat Assessments

If a student does not pass the module they will be required to repeat the CA and/or the exam.

Indicative Syllabus

Module content will address the basis of fundamental elements to body systems. This will be provided in the context of human disease and will broadly cover various areas including:

-Genetic Diseases
- Cardiovascular system and disease
- Neuroscience and neurological disease
- Inflammation and disease

- Neoplasia and carcinogenesis

- Immunology and disease

- Neurodegenerative disease

Coursework & Assessment Breakdown

Coursework & Continuous Assessment
50 %
End of Semester / Year Formal Exam
50 %

Coursework Assessment

Title Type Form Percent Week Learning Outcomes Assessed
1 MCQ Continuous Assessment Open Book Exam 10 % Week 9 1,3
2 Clinical scenario exercises Continuous Assessment Assessment 40 % OnGoing 2,3

End of Semester / Year Assessment

Title Type Form Percent Week Learning Outcomes Assessed
1 Final Exam Final Exam Closed Book Exam 50 % End of Semester 3,4

Full Time Mode Workload

Type Location Description Hours Frequency Avg Workload
Lecture Online Online Lecture 1 Weekly 1.00
Problem Based Learning Online Workshop 2 Weekly 2.00
Independent Learning Not Specified Independent study 4 Weekly 4.00
Total Full Time Average Weekly Learner Contact Time 3.00 Hours

Required & Recommended Book List

Required Reading
2014 Robbins and Cotran Pathologic Basis of Disease W B Saunders Company
ISBN 1455726133 ISBN-13 9781455726134

Dependable, current, and complete, Robbins and Cotran Pathologic Basis of Disease, 9th Edition is the perennially best-selling text that you'll use long after your medical student days are behind you. A world-class author team headed by Drs. Vinay Kumar, Abul Abbas, and Jon Aster, delivers the latest, most essential pathology knowledge in a readable, interesting manner, ensuring optimal understanding of the latest basic science and clinical content. High-quality photographs and full-color illustrations highlight new information in molecular biology, disease classifications, new drugs and drug therapies, and much more. Rely on uniquely authoritative and readable coverage, ideal for USMLE or specialty board preparation, as well as for course work. Simplify your study with an outstanding full-color, highly user-friendly design. Stay up to date with the latest information in molecular and genetic testing and mechanisms of disease. Consult new Targeted Therapy boxes online that discuss drug therapy for specific diseases. Gain a new perspective in key areas thanks to contributions from new authors at the top of their fields. Student Consult eBook version included with purchase. Further your understanding with access to a wealth of interactive ancillaries on the Student Consult site, including pathology case studies and videos and self-assessment questions.

Required Reading
2019-01-11 Rang and Dale's Pharmacology Elsevier
ISBN 0702074489 ISBN-13 9780702074486

Comprehensive yet easy to use, Rang and Dale's Pharmacology has been providing core basic and clinical science information to students and healthcare practitioners worldwide for more than 25 years. The fully revised 9th Edition keeps you up to date with all that's new in the field, including new and emerging drugs and recent studies. From cover to cover, you'll progressively increase your knowledge of all relevant aspects of pharmacology, from a molecular understanding of receptors and drug actions through clinical uses of key groups of drugs. Keeps you up-to-date with new information in this fast-changing field, including significantly revised coverage of CNS drugs, cognitive enhancers, anti-infectives, biologicals/biopharmaceuticals, lifestyle drugs, and more. Includes access to unique features online, including more than 100 brand new chapter-specific multiple-choice questions and 6 new cases for immediate self-assessment. Features a color-coded layout for faster navigation and cross-referencing. Clarifies complex concepts with Key Points boxes, Clinical Uses boxes and full-color illustrations throughout. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references - including 68 bonus dissection videos - from the book on a variety of devices.

Required Reading
2020-06-19 Robbins & Cotran Pathologic Basis of Disease Elsevier
ISBN 032353113X ISBN-13 9780323531139

Module Resources