BIO08051 2016 Formulation Fill Finish and Delivery of Biopharmaceuticals
This module aims to provide students with an understanding of the main considerations in the formulation and fill finish of a biopharmaceutical and also addresses current and emerging drug delivery systems.
On completion of this module the learner will/should be able to;
Formulate and communicate judgements with regard to challenges in the formulation of biopharmaceuticals.
Compare routes of delivery for biopharmaceuticals (e.g. pulmonary, parenteral, transdermal) and evaluate current and novel drug delivery systems designed for biopharmaceuticals.
Explain the principles and applications of typical fill-finish and freeze-drying technologies.
Analyse, evaluate and draw conclusions from data presented in problem solving exercises.
Perform research on a relevant topic and analyse, evaluate and draw conclusions accordingly.
Communicate scientific data in an appropriate format on this topic.
Understand the practical considerations involved in typical fill-finsh operations
Teaching and Learning Strategies
Module Assessment Strategies
The assessment approach for this module will be 100% Continuous Assessment with a range of assessment methods employed including some of the following; short form assessment exams including multiple choice and short answer questions/problems, project assignments/reports, essays and oral presentations. A practical element of this course is also included as part of training in NIBRT.
The miniproject is a MANDATORY form of assessment for any modules on this programme with a miniproject component.
Dependent on the failed element that needs to be repeated.
Dosage forms: Liquid, Frozen liquid, Solid Lyophilized (freeze-dried) etc
Main types of excipients (stabilizers) used in biopharmaceutical formulation.
Packaging materials for biopharmaceuticals
Routes of Administration: Parenteral, Oral, Pulmonary, Nasal, Transdermal etc
Drug Delivery: Controlled release, Targeted delivery and Specialised delivery systems e.g. liposomes, nanoparticles, microparticles.
Coursework & Assessment Breakdown
|Title||Type||Form||Percent||Week||Learning Outcomes Assessed|
|1||Continuous Assessment||Continuous Assessment||Assignment||50 %||OnGoing||1,2,3,4|
|2||Project Presentation||Practical||Project||30 %||End of Term||5,6|
|3||Practical Training NIBRT||Practical||Practical Evaluation||20 %||Week 8||3,4,7|
Distance Learning Mode Workload
|Online Lecture||Distance Learning Suite||Lecture||2||Weekly||2.00|
|Independent Learning||Offsite||Independent Learning||70||Once Per Semester||4.67|
|Practical||Science Laboratory||Laboratory Practicals||8||Once Per Module||0.53|
Protein Formulation and Delivery by E. J. Mc Nally. Publisher; Informa Health Care, New York. Year 2008.
Therapeutic Peptides and Proteins. Formulation, Processing, and Delivery Systems by A. K.
Banga. Second Edition. Publisher Taylor and Francis. Year 2006.