BIO08037 2014 BIOPHARMACEUTICAL SCIENCE PRACTICAL

General Details

Full Title
BIOPHARMACEUTICAL SCIENCE PRACTICAL
Transcript Title
BIOPHARMA PRACTICAL
Code
BIO08037
Attendance
N/A %
Subject Area
BIO - Bio Tech/Eng/Chem
Department
LIFE - Life Sciences
Level
08 - NFQ Level 8
Credit
10 - 10 Credits
Duration
Semester
Fee
Start Term
2014 - Full Academic Year 2014-15
End Term
2019 - Full Academic Year 2019-20
Author(s)
Mary Butler
Programme Membership
SG_SBIOP_E08 201500 Certificate in Science in Bioprocessing Technologies SG_SBIOT_E08 SG_SBIOT_E08 201500 Certificate in Science in Bioprocessing Technologies SG_SBIOT_E08
Description

This Biopharma laboratory practical module will provide students with practical knowledge, know-how and practical skills associated with biopharmaceutical operations. The relevant learning is achieved through the completion of a sequence of laboratory-based and pilot-plant based practicals and experiments that are designed to impart the required expertise. There will also be some research project work associated with the laboratory practicals.

Learning Outcomes

On completion of this module the learner will/should be able to;

1.

Demonstrate a range of practical know-how and skills associated with relevant, lab-based and pilot-plant based upstream bioprocessing equipment.

2.

Demonstrate a range of practical know-how and skills associated with relevant, lab-based and pilot-plant based downstream bioprocessing equipment.

3.

Perform some defined research project work related to the lab. practicals and interpret and critically evaluate the data and results obtained from this project work. 

4.

Take responsibility for and direct the work of other individuals in a quasi-GMP environment.

5.

Demonstrate effective communication skills both orally and in written format.

Teaching and Learning Strategies

as above

Module Assessment Strategies

The assessment strategy will comprise of both observation of skills being acquired as well as formal assessment of knowledge acquisition. There will be a project research element associated with the assessment strategy also.

The miniproject is a MANDATORY form of assessment for any modules on this programme with a miniproject component.

Repeat Assessments

.

Indicative Syllabus

The range of lab-based and pilot-plant based upstream practicals may include some or all of the following items: aseptic techniques; cell culture techniques including cell counting, sub-culturing, thawing up and freezing-down of cells; bioreactor inoculation and operation, sampling and substrate analysis. P ID (Piping and Instrumentation Diagrams) analysis work on bioreactor systems; CIP and SIP cycle operation on bioreactor systems.

 

The range of lab-based and pilot-plant based downstream practicals covered may include some or all of the following items: filter integrity testing; centrifugation; buffer preparation; chromatography; protein concentration using ultrafiltration; protein concentration and buffer exchange using diafiltration; column packing; theory and practice of industrial-scale chromatography skids.

 

The range of lab-based and pilot-plant based aseptic processing practicals may include some or all of the following items: contamination control; vial filling; filling line operation; glove integrity testing and environmental monitoring.

Coursework & Assessment Breakdown

Coursework & Continuous Assessment
100 %

Coursework Assessment

Title Type Form Percent Week Learning Outcomes Assessed
1 Practical Evaluation Observation assessment of practical skills. Continuous Assessment UNKNOWN 20 % Week 1 1,2
2 Open Book Exam Exam at end f day 1 of lab. practicals. Continuous Assessment UNKNOWN 20 % Week 1 1,2,3
3 Open Book Exam Exam at end of day 2 of lab. practicals. Continuous Assessment UNKNOWN 20 % Week 1 1,2,3,4
4 Project Research project based around the lab. practicals. Continuous Assessment UNKNOWN 40 % Week 14 1,2,3,4,5

Part Time Mode Workload


Type Location Description Hours Frequency Avg Workload
Lecture Not Specified Preparatory study material for lab. practicals. 4 Once Per Semester 0.27
Laboratory Practical Science Laboratory Attendance at laboratory practicals. 16 Once Per Semester 1.07
Independent Learning UNKNOWN Research project based on lab. practicals. 3 Weekly 3.00
Total Part Time Average Weekly Learner Contact Time 1.33 Hours

Module Resources

Non ISBN Literary Resources

Walsh, Gary. 'Pharmaceutical Biotechnology'. Wiley. 2007.:-:-#160:::::-:-#160::::

Ratledge, Colin and Kristiansen Bjorn. 'Basic Biotechnology'. Cambridge Press. 2001.

Doran, Pauline M. 'Bioprocess Engineering Principles'. Academic Press. 1995.

Hatti-Kaul, Rajni and Mattiasson, Bo. 'Isolation and Purification of Proteins'. Marcel-Dekker. 2003.:-:-#160::::

Other Resources

None

Additional Information

None