BIO07035 2020 INTRODUCTION TO BIOPHARMACEUTICAL SCIENCE

General Details

Full Title
INTRODUCTION TO BIOPHARMACEUTICAL SCIENCE
Transcript Title
INTRODUCTION TO BIOPHARMACEUTI
Code
BIO07035
Attendance
N/A %
Subject Area
BIO - Bio Tech/Eng/Chem
Department
LIFE - Life Sciences
Level
07 - NFQ Level 7
Credit
05 - 05 Credits
Duration
Semester
Fee
Start Term
2020 - Full Academic Year 2020-21
End Term
9999 - The End of Time
Author(s)
Dr. Michael Barrett DBA (HEM), Mary Heneghan, Yvonne Lang
Programme Membership
SG_SPHAD_B07 201900 Bachelor of Science in Pharmaceutical Science
Description

Introduction to Biopharmaceutical Science will provide the student with a broad overview of the Biopharmaceutical sector.

Learning Outcomes

On completion of this module the learner will/should be able to;

1.

Demonstrate knowledge of the various technologies and disciplines that contribute to Biotechnology and Biopharmaceutical drug target discovery

2.

Identify and describe the different types of Biopharmaceutical products including proteins, antibodies, hormones, nucleic acids etc.

3.

Explain the fundamental techniques of genetic engineering and provide examples of their use in the production of bioproducts.

4.

Evaluate cell models for expression of exogenous gene products and explain the process of gene expression and regulation within these systems.

5.

Compare routes of delivery for biopharmaceuticals (e.g. pulmonary, parenteral, transdermal) and evaluate current and novel drug delivery systems designed for biopharmaceutical products.

Teaching and Learning Strategies

Online delivery and associated facilities/means

Module Assessment Strategies

Assessment of the Introduction to Biopharmaceuticals module will include both continuous assessment and a terminal exam.  Continuous assessment  will involve a range of assessment types including e.g. multiple choice quizzes and small individual project.  The multiple choice quizzes will assess subject knowledge while the small project will allow students to work independently to source, interpret and apply appropriate and referenced literature on a given topic. 

Repeat Assessments

Standard arrangements

Module Dependencies

Prerequisites
None
Co-requisites
None
Incompatibles
None

Indicative Syllabus

Introduction to the most commonly produced biopharmaceutical products and their methods of production.

  • Structure and function of proteins. 
  • Synthesis of proteins.
  • The role of immunology, antibody technologies.
  • The Endocrine System & Biohormones. 
  • Vaccines, Antisense technology & Biosimilars. 

Fundamental techniques of genetic engineering 

  • Cloning
  • PCR
  • Restriction enzymes
  • Vector systems

Expression Systems

  • Process of gene expression and regulation 
  • Cell line selection for optimal protein expression.  
  • Transformation & Transfection technologies

Coursework & Assessment Breakdown

Coursework & Continuous Assessment
40 %
End of Semester / Year Formal Exam
60 %

Coursework Assessment

Title Type Form Percent Week Learning Outcomes Assessed
1 Multiple Choice Continuous Assessment Multiple Choice 20 % OnGoing 1,2,3,4
2 Individual Project Continuous Assessment Project 20 % Week 9 1,2,3,4,5
             

End of Semester / Year Assessment

Title Type Form Percent Week Learning Outcomes Assessed
1 Final Exam Final Exam Closed Book Exam 60 % End of Term 1,2,3
             
             

Online Learning Mode Workload


Type Location Description Hours Frequency Avg Workload
Online Lecture Online Online lecture 2 Weekly 2.00
Total Online Learning Average Weekly Learner Contact Time 2.00 Hours

Module Resources

Non ISBN Literary Resources

Walsh, Gary., Biopharmaceuticals, Wiley, 2003

Ho, R. and Gibaldi, M. Biotechnology and Biopharmaceuticals: Transforming Genes into Drugs, Wiley−Liss, 2003

Brown, T.A., Gene Cloning and DNA Analysis. An Introduction., Oxford Blackwell, 2006

Rick, N.G., Drugs: From Discovery to Approval, Wiley−Liss, 2004

Journal Resources

Relevant scientific journals

URL Resources

As appropriate

Other Resources

None

Additional Information

None