BIO07029 2019 BIOPROCESS ENGINEERING PRACTICAL
This Biopharma laboratory practical module will provide students with practical knowledge, know-how and skills associated with the monitoring and control of modern biopharmaceutical manufacturing systems. The relevant learning is achieved through the completion of a sequence of laboratory-based and pilot-plant based practicals and experiments using dedicated control system test rigs that are designed to impart the required expertise. There will also be some research project work associated with the laboratory practicals.
On completion of this module the learner will/should be able to;
Demonstrate a range of practical know-how and skills associated with relevant practical lab. control and monitoring systems.
Conduct a range of control system experiments based around a dedicated control rig for a modern bioprocessing system.
Follow a sequence of control system instructions for the design and operation of bioprocessing control systems.
Perform some defined research work related to the practical lab. control system work ; interpret and critically evaluate the data and results obtained from this research work in a report document.
Take responsibility for and direct the work of other individuals in a quasi-GMP environment.
Demonstrate effective communication skills both orally and in written format.
Teaching and Learning Strategies
Module Assessment Strategies
A variety of assessment strategies will be employed for this module including the following: quizzes, assignments, lab. reports.
The range of lab-based and pilot-plant based control system practicals may include some or all of the following items: GMP gowning/garbing for cleanroom entry; overview of main control systems for upstream and downstream bioprocesses; the control instrumentation including actuators and sensors for different control loops; the calibration of control instrumentation; the operation and configuration of a HMI (human machine interface) system for control loops; the architecture, operation and programming of a typical PLC system; write a PLC programme using several inputs and outputs for a number of different software functions (timers, counters etc.); develop and test SCADA screens to read/write information for a PLC system.
Coursework & Assessment Breakdown
|Title||Type||Form||Percent||Week||Learning Outcomes Assessed|
|1||Practical Evaluation Observation assessment of practical skills.||Continuous Assessment||UNKNOWN||20 %||Week 1||1,2|
|2||Other Exam Day 1 of Lab. Practicals.||Continuous Assessment||UNKNOWN||10 %||Week 1||1,2,3,4|
|3||Other Exam Day 2 of Lab. Practicals.||Continuous Assessment||UNKNOWN||10 %||Week 1||1,2,3,4|
|4||Written Report Research-based Lab. Report.||Continuous Assessment||UNKNOWN||60 %||End of Term||4,5,6|
Part Time Mode Workload
|Lecture||Not Specified||Preparatory study material.||4||Once Per Semester||0.27|
|Laboratory Practical||Science Laboratory||Attendance at laboratory practicals.||16||Once Per Semester||1.07|
|Independent Learning||UNKNOWN||Lab. Practical Report Document.||3||Weekly||3.00|
Doran, P.M., Bioprocess Engineering Principles, Academic Press, 2006.
http://www.cheric.org/educational/control (Introduction to process control; understand the measurements - DP cell; Understand the actuator - control valve; PID controller tuning using various methods; Open loose response in the time and frequency domains; Closed loop PID response and stability; Feedforward and cascade control.)
http://www.pc-education.mcmaster.ca/instrumentation/go_inst.htm (Sensors, instrumentation and control valves).