BIO07027 2019 BIOPROCESS ENGINEERING THEORY

General Details

Full Title
BIOPROCESS ENGINEERING THEORY
Transcript Title
BIOPROCESS ENGINEERING THEORY
Code
BIO07027
Attendance
N/A %
Subject Area
BIO - Bio Tech/Eng/Chem
Department
LIFE - Life Sciences
Level
07 - NFQ Level 7
Credit
05 - 05 Credits
Duration
Stage
Fee
Start Term
2019 - Full Academic Year 2019-20
End Term
9999 - The End of Time
Author(s)
Paul Walsh
Programme Membership
SG_SBIOP_J07 201900 Bachelor of Science in Science in Biopharmaceutical Science SG_SBIOE_E07 201900 Certificate in Science in Bioprocess Engineering L7
Description

This module aims to provide the student with a fundamental understanding of the key  elements of bioprocess engineering control systems and the key role they play in the processing of modern biopharmaceutical products.  

Learning Outcomes

On completion of this module the learner will/should be able to;

1.

Explain the business case and overall critical importance for the design of process control systems in bioprocessing.

2.

Outline the main control system components including process controllers, actuators, feedback sensors etc.

3.

Explain the operation of a modern PLC system, how the inputs and outputs are connected to it and how a programme is executed from it.

4.

Discuss the principal monitoring and control systems in use for biopharmaceutical processes.

5.

Explain the role and operation of SCADA (supervisory control and data acquisition) systems for modern bioprocessing.

Teaching and Learning Strategies

N/A

Module Assessment Strategies

A variety of assessment strategies will be employed for this module including the following: online exams/quizzes, assignments, final written exam paper.

Repeat Assessments

N/A

Indicative Syllabus

Process control and monitoring is a critical feature of the modern biopharmaceutical operation becasuse of the strict regulatory requirements on product release. Its applications range from status monitoring of a simple system to continuous or batch process control and reporting of a complex bioreactor process. All of these topics are explored in this module which starts with an overview of a typical control system and its principla components. The programme material will include the some or all of the following topics:

  • The business case and strategic perspective for using process monitoring and control.
  • The design and implementation of control system components including process controllers, actuators, valves etc.
  • The analysis of a variety of practical process control design strategies.
  • The main bioprocess control loops with associated equipment and control technologies.
  • The architecture, operation and programming of a typical PLC system.
  • The application of PLC control theory for a typical bioreactor control system.
  • SCADA systems, their design and application for bioprocessing control and monitoring.

 

Coursework & Assessment Breakdown

Coursework & Continuous Assessment
50 %
End of Semester / Year Formal Exam
50 %

Coursework Assessment

Title Type Form Percent Week Learning Outcomes Assessed
1 Multiple Choice Questions Continuous Assessment Multiple Choice 10 % Week 5 1,2,3,4,5
2 Multiple Choice Questions Continuous Assessment Multiple Choice 20 % Week 10 4,5
3 SAQ Continuous Assessment Assessment 20 % Week 13 1,2,3,4,5

End of Semester / Year Assessment

Title Type Form Percent Week Learning Outcomes Assessed
1 Final Exam Final Exam Closed Book Exam 50 % End of Term 1,2,3,4,5
             
             

Part Time Mode Workload


Type Location Description Hours Frequency Avg Workload
Lecture Not Specified Online 1 Weekly 1.00
Directed Learning Not Specified Course Notes/Slides 3 Weekly 3.00
Independent Learning UNKNOWN Mini Research Assignment 3 Weekly 3.00
Total Part Time Average Weekly Learner Contact Time 4.00 Hours

Module Resources

Non ISBN Literary Resources

Doran, P.M., Bioprocess Engineering Principles, Academic Press, 2006.

Journal Resources

N/A

URL Resources

N/A

Other Resources

http://www.cheric.org/educational/control   (Introduction to process control; understand the measurements - DP cell; Understand the actuator - control valve; PID controller tuning using various methods; Open loose response in the time and frequency domains; Closed loop PID response and stability; Feedforward and cascade control.)

http://www.pc-education.mcmaster.ca/instrumentation/go_inst.htm  (Sensors, instrumentation and control valves).

Additional Information

None