BIO07022 2019 PROTEIN BIOTECHNOLOGY

General Details

Full Title
PROTEIN BIOTECHNOLOGY
Transcript Title
PROTEIN BIOTECHNOLOGY
Code
BIO07022
Attendance
N/A %
Subject Area
BIO - Bio Tech/Eng/Chem
Department
LIFE - Life Sciences
Level
07 - NFQ Level 7
Credit
05 - 05 Credits
Duration
Semester
Fee
Start Term
2019 - Full Academic Year 2019-20
End Term
9999 - The End of Time
Author(s)
Macdara Bodeker
Programme Membership
SG_SBIOM_B07 201900 Bachelor of Science in Biomedical Science SG_SMEDI_H08 201900 Bachelor of Science (Honours) in Science in Medical Biotechnology
Description

This module aims to study the structure and function of proteins in greater depth than the basics covered in a Biochemistry module.  Protein primary, secondary, tertiary and quaternary structure will be examined using non traditional methods.. There is a heavy emphasis on using bioinformatics and data mining technologies to gain an understanding of protein design and genetic manipulation.

Learning Outcomes

On completion of this module the learner will/should be able to;

1.

List and explain the major bond types which accompany peptide and protein formation and understand what conditions need to be maintained to preserve their structure.

2.

Illustrate and distinguish between the main secondary, tertiary and quaternary structures which are formed during protein synthesis and also the role and significance of post translational modifications.

3.

Examine the key functions of proteins in cells and tissues and the characterize the role of proteins in human disease.

4.

Demonstrate an ability to search and compare DNA and protein sequences and structures from sequencing databases using data mining techniques.

5.

Demonstrate an ability to write industry standard reports with particular emphasis on effective referencing and prioritisiation/selection of relevant material. 

Teaching and Learning Strategies

'This module will be delivered fulltime. This will include lectures and computer laboratory practicals augmented by independent learning and directed learning. This approach is expected to address student learning needs. Moodle will be used as a repository of educational resources and as a means of assessment (e.g. quizzes, uploading assignments and journals).

Module Assessment Strategies

This module is 100% Continuous Assessment. There will be 3 number of MCQs given during the semester every four weeks. A written summary of a chosen peer reviewed article on protein will be submitted at the end of the semester. A project on a specific recombinant protein is submitted at the end of the semester which demonstrates the student's ability to critically evaluate an aspect of recombinant protein design and production.

Repeat Assessments

Repeat Continuous Assessment and/or project resubmission.

Module Dependencies

Prerequisites
Biochemistry.
Co-requisites
None
Incompatibles
None

Indicative Syllabus

Protein Structures

 

Protein bonding

 

Structural Domains

 

Protein adverse reactions

 

Post-translational modification

 

Protein Functions and protein as drugs

 

Proteins and Disease

 

Protein Modelling

Coursework & Assessment Breakdown

Coursework & Continuous Assessment
100 %

Coursework Assessment

Title Type Form Percent Week Learning Outcomes Assessed
1 Theory quizzes. Continuous Assessment Multiple Choice 45 % Any 1,2,3
2 Group Project Group \Discussion of Protein Relevant Topics Formative Group Project - % Any 1,2,3,4,5
3 Literature Survey Continuous Assessment Written Report 15 % End of Semester 4,5
4 Individual Project Topical Individual Research Project Written Report 40 % End of Semester 1,2,3,4,5

Full Time Mode Workload


Type Location Description Hours Frequency Avg Workload
Lecture Tiered Classroom Lecture 2 Weekly 2.00
Independent Learning Not Specified Self Study 5 Weekly 5.00
Total Full Time Average Weekly Learner Contact Time 2.00 Hours

Module Resources

Non ISBN Literary Resources

Introduction to protein science: Architecture, function and genomics. Arthur M.Lesk. Oxford University Press 1st ed. 2004

Protein Biochemistry and Proteomics, Hubert Rehm. Oxford University Press 2006

Journal Resources

none

URL Resources

www.ncbi.nlm.nih.gov

www.ebi.ac.uk

Other Resources

Moodle lecture series

The Theoretical and Computational Biophysics Group (TCBG), an NIH Resource for Macromolecular Modeling and Bioinformatics: http://www.ks.uiuc.edu/

Medline protein/peptide databases

Additional Information

None