BIO07015 2019 Bioanalytial Techniques L7 Practical.

General Details

Full Title
Bioanalytial Techniques L7 Practical.
Transcript Title
Bioanalytial Techniques L7 Pra
Code
BIO07015
Attendance
N/A %
Subject Area
BIO - Bio Tech/Eng/Chem
Department
LIFE - Life Sciences
Level
07 - NFQ Level 7
Credit
05 - 05 Credits
Duration
Semester
Fee
Start Term
2019 - Full Academic Year 2019-20
End Term
9999 - The End of Time
Author(s)
Sharon Barrett, Paul Walsh
Programme Membership
SG_SBIOP_J07 201900 Bachelor of Science in Science in Biopharmaceutical Science
Description

This module aims to provide students with a broad knowledge of the practice of the various pharmacopoeia test methods and associated laboratory instrumentation routinely employed in a Biopharmaceutical Quality Control laboratory to assess the quality of raw materials, intermediate and finished-goods product.      

Learning Outcomes

On completion of this module the learner will/should be able to;

1.

Interpret the European Pharamcopoeia and US Pharmacopoeia for QC Testing.  

2.

Outline and evaluate the common test methods routinely employed in the analysis of pharmaceutical and biopharmaceutical products.

3.

Describe the typical analytical equipment employed for performance of the analytical test methods.

4.

Perform a range of analysis lab. experiments and outline and evaluate the equipment requirements for performance of the various test methods.  

5.

Demonstrate understanding of how to  interpret data from both qualitative and quantitative analytical techniques using GLP as would be required in a QC laboratory.  

6.

Analyse  and draw conclusions from typical data obtained in an analytical laboratory and/or data presented in problem solving exercises.

Teaching and Learning Strategies

N/A

Module Assessment Strategies

A combination of continuous assessment strategies, some laboratory experiments and an end-of-term exam.

Repeat Assessments

N/A

Indicative Syllabus

The following is a summary indication of the main topics included in this module:

Introduction to GLP, GMP and ISO 17025.  

Conduct a series of laboratory-based experiments in the following area of QC analysis: 

  •    pH calibration and measurements.
  •    Conductivity measurements.
  •    Melting point.
  •    Osmolality measurements.
  •    Titrations.
  •    Loss on drying.
  •    Residue on Ignition.
  •    Heavy Metals tests.
  •    Optical rotation.
  •    Particle size analysis.
  •    Viscosity.
  •    Relative density.
  •    HPLC – Principles and Applications.   
  •    Protein Electrophoresis.
  •    Immunoassays and protein assays.
  •    Introduction to PCR equipment. 

 

 

 

 

Coursework & Assessment Breakdown

Coursework & Continuous Assessment
100 %

Coursework Assessment

Title Type Form Percent Week Learning Outcomes Assessed
1 Continuous Assessment Short-form exams and lab. experiments write-ups. Continuous Assessment Assessment 100 % OnGoing 1,2,3,4,5,6
             
             

Part Time Mode Workload


Type Location Description Hours Frequency Avg Workload
Lecture Distance Learning Suite Online lecture. 1 Weekly 1.00
Laboratory Practical Science Laboratory Lab.-based experimetns. 16 Once Per Semester 1.07
Total Part Time Average Weekly Learner Contact Time 2.07 Hours

Module Resources

Non ISBN Literary Resources

Protein Biochemistry and proteomics: Publisher: Elsevier ISBN: 978-0-12-088545-9.

Pharmaceutical Biotechnology: An Introduction for Pharmacists and Pharmaceutical Scientists, 2nd Edition. J. Daan and R. Sindelar. Publisher: Taylor and Francis. ISBN: 0415285003.

Journal Resources

N/A

URL Resources

N/A

Other Resources

None

Additional Information

None