BIO06023 2018 INTRODUCTION TO BIOPHARMACEUTICALS

General Details

Full Title
INTRODUCTION TO BIOPHARMACEUTICALS
Transcript Title
BIOPHAMACEUTICALS 1
Code
BIO06023
Attendance
N/A %
Subject Area
BIO - Bio Tech/Eng/Chem
Department
LIFE - Life Sciences
Level
06 - NFQ Level 6
Credit
05 - 05 Credits
Duration
Semester
Fee
Start Term
2018 - Full Academic Year 2018-19
End Term
2019 - Full Academic Year 2019-20
Author(s)
Ioannis Manolakis, Mary Heneghan
Programme Membership
SG_SPHAR_C06 201300 Higher Certificate in Science in Pharmaceutical Science
Description

Introduction to Biopharmaceuticals will provide the student with a broad overview of the Biopharmaceutical sector.

Learning Outcomes

On completion of this module the learner will/should be able to;

1.
Describe the history, development and future prospects of the Biopharmaceutical and Biotechnology industries in Ireland, the EU and worldwide.
2.

Demonstrate knowledge of the various technologies and disciplines that contribute to Biotechnology and Biopharmaceutical drug target discovery. 

3.

Identify and describe the different types of Biopharmaceutical products including proteins, antibodies, hormones, nucleic acids etc. 

4.

Explain the fundamental techniques of genetic engineering and provide examples of their use in the production of bioproducts.

5.

Evaluate cell models for expression of exogenous gene products and explain the process of gene expression and regulation within these systems.

6.

Effectively communicate scientific knowledge in an appropriate format.

Module Assessment Strategies

Assessment of the Introduction to Biopharmaceuticals module will include both continuous assessment and a terminal exam.  Continuous assessment  will involve a range of assessment types including multiple choice quizzes, a small individual project and a series of classroom based assignments.  The multiple choice quizzes will assess subject knowledge while the small project will allow students to work independently to source, interpret and apply appropriate and referenced literature on a given topic. The classroom based assignments will include computer based practical's designed to employ advanced data analysing, synthesising and summarising skills in a scientific work setting. 

Module Dependencies

Prerequisites
None
Co-requisites
None
Incompatibles
None

Indicative Syllabus

The history, development and future prospects of the Biopharmaceutical and Biotechnology industry.

Applications of Biotechnology in Biopharmaceutical medicine.

Introduction to the most commonly produced biopharmaceutical products and their methods of production.

  • Structure and function of proteins. 
  • The role of immunology, antibody technologies and  immunodiagnostics. 
  • The Endocrine System & Biohormones. 
  • Vaccines, Antisense technology & Biosimilars. 

Fundamental techniques of genetic engineering 

  • Cloning
  • PCR
  • Restiction enzymes
  • Vector systems

Expression Systems

  • Process of gene expression and regulation 
  • Cell line selection for optimal protein expression.  
  • Transformation & Transfection technologies
  • Cell banking. 

 

 

Coursework & Assessment Breakdown

End of Semester / Year Formal Exam
100 %

Coursework Assessment

Title Type Form Percent Week Learning Outcomes Assessed
1 Multiple Choice Continuous Assessment UNKNOWN 30 % OnGoing 1,2,3,4,5
2 Individual Project Continuous Assessment UNKNOWN 20 % Week 9 3,6
3 Continuous Assessment Continuous Assessment UNKNOWN 10 % OnGoing 1,2,3,4,5

End of Semester / Year Assessment

Title Type Form Percent Week Learning Outcomes Assessed
1 Final Exam Final Exam UNKNOWN 40 % End of Term 1,2,3,4,5
             
             

Full Time Mode Workload


Type Location Description Hours Frequency Avg Workload
Lecture Tiered Classroom Lecture 2 Weekly 2.00
Group Learning Flat Classroom Group Learning 1 Weekly 1.00
Independent Learning UNKNOWN Self Study 4 Weekly 4.00
Total Full Time Average Weekly Learner Contact Time 3.00 Hours

Module Resources

Non ISBN Literary Resources

Walsh, Gary., Biopharmaceuticals, Wiley, 2003

Ho, R. and Gibaldi, M. Biotechnology and Biopharmaceuticals: Transforming Genes into Drugs, Wiley−Liss, 2003

Brown, T.A., Gene Cloning and DNA Analysis. An Introduction., Oxford Blackwell, 2006

Rick, N.G., Drugs: From Discovery to Approval, Wiley−Liss, 2004

Other Resources
None
Additional Information

None